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Search all Publications of Villunger A.
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Selected Publications |
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2011 - Grespi F, Ottina E, Yannoutsos N, Geley S, Villunger A.
Generation and evaluation of an IPTG-regulated version of Vav-gene promoter for mouse transgenesis |
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2011 - Bock FJ, Villunger A.
GSK3 TIPping off p53 to unleash PUMA. |
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2011 - Baumgartner F, Villunger A.
Apoptosis: a barrier against cancer no more? |
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2010 - Verena Labi, Miriam Erlacher, Gerhard Krumschnabel, Claudia Manzl, Alexandar Tzankov, Josephina Pinon, Alexander Egle and Andreas Villunger (2010)
Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation |
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2010 - Anna Frenzel, Verena Labi, Waldemar Chmelewskij, Christian Ploner, Stephan Geley, Heidelinde Fiegl, Alexander Tzankov and Andreas Villunger (2010)
Suppression of B cell lymphomagenesis by the BH3-only proteins Bmf and Bad |
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2010 - Tischner D, Woess C, Ottina E, Villunger A.
Bcl-2-regulated cell death signalling in the prevention of autoimmunity. |
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2010 - Wiegers GJ, Kaufmann M, Tischner D, Villunger A.
Shaping the T-cell repertoire: a matter of life and death. |
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2010 - Labi V, Villunger A.
PUMA-mediated tumor suppression: A tale of two stories. |
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2010 - Grespi F, Soratroi C, Krumschnabel G, Sohm B, Ploner C, Geley S, Hengst L, Häcker G, Villunger A.
BH3-only protein Bmf mediates apoptosis upon inhibition of CAP-dependent protein synthesis. |
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2010 - Villunger A.
Only the strong survive. |
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2010 - Krumschnabel G, Ebner HL, Hess MW, Villunger A.
Apoptosis and necroptosis are induced in rainbow trout cell lines exposed to cadmium. |
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2009 - Krumschnabel G, Sohm B, Bock F, Manzl C, Villunger A. (2009)
The enigma of caspase-2: the laymen's view. |
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2009 - Claudia Manzl, Gerhard Krumschnabel, Florian Bock, Benedicte Sohm, Verena Labi, Florian Baumgartner, Emmanuelle Logette, Jürg Tschopp and Andreas Villunger (2009)
Caspase-2 activation in the absence of PIDDosome formation |
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2009 - Manzl C, Krumschnabel G, Bock F, Sohm B, Labi V, Baumgartner F, Logette E, Tschopp J, Villunger A. (2009)
Caspase-2 activation in the absence of PIDDosome formation |
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2008 - Michalak EM, Villunger A, Adams JM, Strasser A. (2008)
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute. |
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2008 - Labi V, Grespi F, Baumgartner F, Villunger A (2008)
Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy? |
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2008 - Verena Labi, Miriam Erlacher, Stephan Kiessling, Claudia Manzl, Anna Frenzel, Lorraine A O`Reilly, Andreas Strasser and Andreas Villunger (2008)
Loss of the BH3-only protein bmf impairs B cell homeostasis and accelerates g-radiation-induced thymic lymphoma development” |
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2008 - Hermann-Kleiter N, Gruber T, Lutz-Nicoladoni C, Thuille N, Fresser F, Labi V, Schiefermeier N, Warnecke M, Huber L, Villunger A, Eichele G, Kaminski S, Baier G. (2008)
The Nuclear Orphan Receptor NR2F6 Suppresses Lymphocyte Activation and T Helper 17-Dependent Autoimmunity |
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2008 - Ploner C, Kofler R, Villunger A. (2008)
Noxa: at the tip of the balance between life and death. |
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2008 - Piñon JD, Labi V, Egle A, Villunger A. (2008)
Bim and Bmf in tissue homeostasis and malignant disease. |
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2008 - Labi V, Erlacher M, Manzl C, Frenzel A, O´Reilly L, Strasser A, Villunger A (2008)
Targeted deletion of the BH3-only protein gene bmf causes defects in B cell homeostasis and accelerates g-radiation-induced thymic lymphoma development |
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2007 - Naik E, Michalak EM, Villunger A, Adams JM, Strasser A (2007)
Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa. |
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2007 - Hamrouni A, Olsson A, Wiegers GJ, Villunger A (2007)
Impact of cellular lifespan on the T cell receptor repertoire. |
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2007 - Olsson A, Manzl C, Strasser A, Villunger A.(2007)
How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?
Cell Death Differ. 2007 Sep;14(9):1561-75. |
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2007 - Ekoff M, Kaufmann T, Engstrom M, Motoyama N, Villunger A, Jonsson JI, Strasser A, Nilsson G. (2007)
The BH3-only protein Puma plays an essential role in cytokine deprivation-induced apoptosis of mast cells. |
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2006 - Anette Bauer, Andreas Villunger, Verena Labi, Silke F. Fischer, Andreas Strasser, Hermann Wagner, Roland M. Schmid and Georg Häcker (2006)
The NF-kappa B Regulator Bcl-3 and the BH3-Only Proteins Bim and Puma Control the Death of Activated T Cells |
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2006 - Teis D, Taub N, Kurzbauer R, Hilber D, de Araujo ME, Erlacher M, Offterdinger M, Villunger A, Geley S, Bohn G, Klein C, Hess MW, Huber LA (2006)
p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis. |
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2006 - Labi V, Erlacher M, Kiessling S and Villunger A (2006)
BH3-only proteins in cell death initiation, tumor suppression and anticancer therapy |
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2006 - Kiessling S, Lutz C, Olsson A, Niederegger H, Baier G, and Villunger A (2007)
Compensatory mechanisms regulate the Bcl-2 rheostat and lymphocyte survival in the absence of Akt1/PKB? |
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2006 - You H, Pellegrini M, Tsuchihara K, Yamamoto K, Haecker G, Erlacher M, Villunger A and Mak TW (2006)
FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal |
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2006 - Akhtar R, Geng Y, Klocke BJ, Latham CB, Villunger A, Michalak E, Strasser A, Caroll S, Roth KA (2006)
BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediated neuronal precursor cell death |
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2006 - Kuroda J, Puthalakath H, Cragg M, Kelly PN, Bouillet P, Huang DCS, Kimura S, Ottmann O, Druker B, Villunger A, Roberts AW and Strasser A (2006)
Pro-Apoptotic BH3-Only Proteins Bim and Bad Mediate Imatinib-Induced Killing of Bcr/Abl+ Leukemic Cells and Resistance due to their Loss Is Overcome by a BH3 Mimetic |
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2006 - Concannon CG, Koehler BF, Reimertz C, Murphy BM, Bonner C, Thurow N, Ward MW, Villunger A, Strasser A, Kogel D, Prehn JH. (2006)
Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway. |
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2006 - Erlacher M, Labi V, Manzl C, Böck G, Tzankov A, Michalak E, Strasser A, Villunger A. (2006)
Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction. |
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2006 - Kuroda J, Puthalakath H, Cragg MS, Kelly PN, Bouillet P, Huang DC, Kimura S, Ottmann OG, Druker BJ, Villunger A, Roberts AW, Strasser A. (2006)
Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic. |
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2006 - Erlacher M, Labi V, Manzl C, Böck G, Tzankov A, Michalak E, Strasser A, Villunger A (2006)
Bim is the rate-limiting BH3-only protein triggering cell death during lymphocyte development but it cooperates with PUMA in factor deprivation- and genotoxic stress-induced apoptosis |
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2005 - Erlacher M, Coultas L, Michalak M, Labi V, Niederegger H, Kelly P, Adams J, Strasser A, and Villunger A (2005)
The BH3-only proteins PUMA and Bim are rate-limiting for gamma-radiation and glucocorticoid-induced lymphocyte apoptosis of lymphoid cells in vivo |
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2005 - Wong HK, Fricker M, Wyttenbach A, Villunger A, Michalak A, Strasser A and Tolkovsky AM (2005)
Mutually-exclusive subsets of BH3-only proteins are activated by the p53 and JNK/c-Junsignaling pathways during cortical neuron apoptosis induced by arsenite |
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2005 - Michalak E, Villunger A, Erlacher M and Strasser A (2005)
Death Squads Enlisted by the Tumour Suppressor P53 |
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2005 - Tan TT, Degenhardt K, Nelson DA, Beaudoin B, Nieves-Neira W, Bouillet P, Villunger A, Adams JM, White E. (2005)
Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy. |
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2005 - Kirschnek S, Ying S, Fischer S, Häcker H, Villunger A, Hochrein H and Häcker G (2005)
Phagocytosis-induced Apoptosis requires Up-Regulation and Activation of the BH3-only Protein Bim and can be blocked by Bcl-2 overexpression |
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2004 - Villunger A, Marsden VS, Erlacher M, Bouillet P, Lew A, Zhang Y, Berzins S, Godfrey D, Heath WR and Strasser A (2004)
Negative Selection of Semi-Mature CD4+8-HSA+ Thymocytes Requires the BH3-Only Bcl-2 Family Member Bim but is independent of death receptor signaling |
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2003 - Villunger A, Michalak E, Coultas L, Müllauer F, Böck G, Ausserlechner MJ, Adams J and Strasser A (2003)
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa |
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2003 - Villunger A. Marsden V and Strasser A (2003)
Efficient T cell receptor-mediated apoptosis in nonobese diabetic mouse thymocytes |
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2003 - Villunger A, Scott C, Bouillet P and Strasser A (2003)
Essential role for the BH3-only protein Bim, but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival |
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